It happens to many. Thyroidectomy or radioactive ablatement will make you hypothyroid and should be a last resort if remission fails and you can't restart Carbimazole. I went back over active in January, this is the 4th time. Thank you for your advice, I spoke to a lady where I worked who said similar to what you have, she was extremely poorly on carbimazole and had to come off it and in the end had her thyroid out, I am starting to wonder if maybe this is the way forward I'm not too sure. how much weight will i gain on carbimazole ? Thyroidectomy or radioactive ablatement will make you hypothyroid and should be a last resort if remission fails and you can't restart Carbimazole. So essentially my choices were to deal with the weight gain, or start popping pills to manage the side effects … This might be the best choice for you in the long term, but I'm just wondering why you think Carbimazole may not be right for you ? This has made a real difference - the continuity has been successful and I have been able to build a relationship (to some extent) with one person. i started taking carbimazole for my... View answer Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Though less serious than other side effects, contact your doctor if any of these side effects become more bothersome or regularly occur. Hyperthyroidism causes weight loss!. Living with a galloping metabolism isn't viable in the long term, for one thing, you could end up damaging your heart. The starting dose of Felimazole Coated Tablets is 2.5 mg administered every 12 hours. Make new blood tests and maybe your future includes adding Levo to your daily routine (besides Carbi). Once your thyroid is removed completely or destroyed by iodine treatment - you are, from that point, having to artificially replace the hormones. Thank you, I will post my results when I've had them done tomorrow and see what people think, to be honest I thought everything was under control but the tsh level isn't right which does concern me a little and I can'tget my head around it at all. I'm 51 and work in the media. Also if it is found that you do have Graves, having a thyroidectomy does not change that - you will still have Graves, which may manifest in other ways. If you are hyper, it can be vanishingly low, and it may take a while to bounce back once you've started treatment. Hugs. This study showed that among 42 patients with Graves' disease that the average weight gain was around 12 pounds after starting Methimazole. Feeling sick (nausea) Headache or feeling dizzy; Skin rashes; Itching; Stomach upset ; Painful joints; Hair thinning; Changes to your taste. Carbimazole inhibits thyroxine so if you have too much of it, I guess it could make you feel like your thyroid is underactive, which would explain the exhaustion you're feeling. The mother could then be treated with carbimazole from the second trimester throughout the remainder of the pregnancy, reducing the time of exposure of mother and fetus to the potentially hepatotoxic effects of propylthiouracil. If you are slowly getting better results with carbimozole and have been fortunate not to develop Thyroid Eye Disease then you should continue with that. I was told to watch out for a fever and sore throat, something to do with white blood cells. Other side effects include: pruritus, speech disturbance, amblyopia, and xerostomia. I went totally gluten free a couple of years ago and have totally reduced my thyroid antibody levels. Do you know what your B12, vitamin D, ferritin and folate levels are as well as your thyroid results and what are your antibodies like now? Dose adjustments should be made in 2.5 mg increments. The most common side effects are feeling sick, upset stomach, headache, joint pain, skin rash and itching. Answered by Dr. Bhavin Patel: Stopping may cause: Stopping the medication may worsen your symptoms. Once diagnosed - I was on carbimozole and propranolol plus various treatments for the eye disease. I am coming off the stuff as I'd rather be dead than fat and will tell him that. These side effects may go away during treatment as your body adjusts to the medicine. I have been taking 75mcgs of T3 only for two and a half years. But probably better than surgeons playing with you, Hi sorry to hear your gaining weight so fast , I understand its so depressing. Iodine treatment and total thyroid removal are not a solution and should be the last resort. Please don't even think about RAI or surgery its only a quick route to life long meds and a feeling of will I ever feel better being hypo. If Carbi is working for you, controlling your hormones level, you are one of the lucky ones! If so, it may be Thyroid Eye Disease which is made worse by RAI. I now eat less than I did before but a much healthier diet. If you don't have Graves disease there is a good chance of permanent remission of hyperthyroidism after 9-18 months. Just a thought. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. There is a serious risk of permanent heart damage and osteoporosis when hyperthyroidism is not treated. Symptoms were heart palpitations, hair loss, brain fog, painful joints (esp. i was diagnosed with HyperT around a month ago and at diagnosis had a T4 reading of 38.8. If you have to have your thyroid removed or zapped with RAI, you are likely to be hypo for the rest of your life. Mostly of muscle tissue, which is why your thigh muscles become weak. Carbimazole may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. Hyperthyroidism can cause weight gain so stopping Carbimazole may not help anyway. I'm worried about the side effects. Before using Carbimazole, inform your doctor about your current list of medications, over the counter products (e.g. This means they can get a bit worked up when it's well outside range. Rate Carbimazole to receive MedCheck, Discover best treatments based on user reviews of side effects, efficacy, health benefits, uses, safety and medical advice. Remember you have a thyroid for a reason - with good consistent treatment, good diet, exercise and sleep you could stabilise it and get it to work for you not against you. Once Carbi becomes a problem then you have very few options. My advice is please don’t use your carbimozole dose as a weight loss aid. They prescribed synthroid. I’ve also started increasing my activity, which I can now do as I’m not exhausted all the time. The half-life may be prolonged due to the liver disorder. Type: Prescribing and Technical Information (Add filter) See below for a comprehensive list of adverse effects. I had Graves in 2008 and unfortunately I developed the worst allergic reactions to Carbi and ended up in a hospital for some days under full-time observation... the worst experience ever (that is another story). Common side effects which have been reported by users of Carbimazole include dizziness, drowsiness, headache, pain in the joints, nausea, vomiting, upset stomach, muscle pain, taste changes and numbness. Blood tests should point to this. legs), chronic fatigue, shakiness, hot flushes, freezing cold, eye problems (later diagnosed as thyroid eye disease) etc etc. The most common adverse effects associated with carbimazole administration are gastrointestinal signs (Bucknell, 2000). Carbimazole is used to treat hyperthyroidism. I have been diagnosed with hyperthyroidism and was given Carbimazole as the long term medication. We know from studies such as this, that it is NOT uncommon for patients to gain around 5kg or 12 pounds when they start Methimazole (5). Long story short, they took a blood test and I was no longer within normal limits. This is partly why I became exasperated with the endo dept at my hospital (Whittington - North London) as they kept tweaking and messing with my treatment - often only looking at half the picture whilst at the same time constantly saying they could whip out my thyroid, if I’d prefer. As long as you have your thyroid there remains the possibility to either stabilise it or for your Graves to go into remission. I avoid gluten and drink loads of water. I won’t bore you with the long bumpy road of dealing with endos who were at times down ‘right dangerous’ through ‘less than useless’ to ‘okay’, but finally I have my thyroid under control. A couple years have met a woman whose sister died from Carbi allergy (in Denmark). As my metabolism slowed down, my appetite has been slower to follow ! Help with weight gain/trouble losing from thyroid being out of whack. The other drug acted on me the same way as Carbi and I had no alternative but Radio Iodine or surgery. You dont want to mess up with it. Start studying side effects. If abnormal liver function is discovered, the treatment should be stopped. I am starting to consider to stop taking the medication as I really can't face it & just feel like I am replacing one health problem with another. However, I did gain 2.5 stone once I started carbimozole. Carbimazole :: Weight Gain. I have been on Carbimazole for only about a month and have started to gain weight. While this can be treated relatively easily with levo, you're just as likely to find it difficult to lose weight while you're hypo, if not more so. I read that you go back to your pre Graves weight. GPs (rightly or not) tend to use TSH alone when monitoring people who are hypothyroid, which is their main exposure to thyroid disease. Weight gain has been reported as one of the possible side effects. 18-24 months off carbizole then same again. My son is hyper and painfully thin but put on weight on carbinizole but after a year has gone into remission and is ok now. I was on steroids and could do a thing because my heart was literally exhausted. You may have to starting taking some Levo. Carbimazole is associated with an increased risk of congenital malformations, especially when administered in the first trimester of pregnancy and at high doses. I have today been diagnosed for the 2nd time with an overactive thyroid. Other side effects include: If you get any of the following side effects, they normally go away while you keep taking your medicine. Keep gaining weight and can't shift it help. Hi again. Its not the Carbimazole itself that makes you gain weight, it's the effect it has on your thyroid gland. Carbi is a pill and a non extreme way to control Graves. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. He told me the next steps were to take Carbizamole for the next 18 months. Carbimazole :: Stopping Carbimazole - Started To Gain Weight May 21, 2009. Hi, Thank you your reply it sounds like we had very similar symptoms and you have experienced the same issues with endocrine, being either useless or just Ok, I'm pleased to hear that weight loss can be achieved but more importantly to stay a good healthy weight and eat a healthy diet makes me feel a bit more reassured, I'm just a little frustrated with endocrine as I seem to get different stories every time I see them, they have not really talked about my tsh levels but my gp is concerned as they are very low at 0.02 but I'm going to discuss this with endo tomorrow as have an appointment with them and hopefully I will get some answers from them, I don't understand how they can say I am stable on carbimazole if my tsh is clearly saying everything is not as it should be, Thank you so much for your help and advice. On 40mg, usual procedure is slow reduction down to 5mg, takes 18-24 months. Removal or iodine treatment should always be absolute last resort when all else has failed. My main symptoms went (shaking, palpitations, anxiety, and generally feeling rubbish). Have they checked for antibodies it will tell you if you have graves or hashimios. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Has anyone experienced anything similar or have any advice? Good to hear that a gluten free diet has helped balance / maintain thyroid balance. Other side-effects you need to know about. At the time of diagnosis my thyroid was out of control. I took the decision to stop them as I suffered from some of the side effects and my white blood cells were being affected. 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